2-Aryl-4,5,6,7-tetrahydro-1,3-benzothiazol-7-ols as a class of antitumor agents selectively active in securin(-/-) cells.

Zhang, Nan

2-Aryl-4,5,6,7-tetrahydro-1,3-benzothiazol-7-ols as a class of antitumor agents selectively active in securin(-/-) cells. [electronic resource] - Bioorganic & medicinal chemistry letters Jul 2010 - 3903-5 p. digital

Publication Type: Journal Article

1464-3405

10.1016/j.bmcl.2010.05.021 doi


Aneuploidy
Antineoplastic Agents--chemical synthesis
Benzothiazoles--chemical synthesis
Cell Line, Tumor
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Humans
Molecular Structure
Neoplasm Proteins--antagonists & inhibitors
Securin
Stereoisomerism
Structure-Activity Relationship