Anti-inflammatory effects of pioglitazone on iron-induced oxidative injury in the nigrostriatal dopaminergic system.

Yu, H C

Anti-inflammatory effects of pioglitazone on iron-induced oxidative injury in the nigrostriatal dopaminergic system. [electronic resource] - Neuropathology and applied neurobiology Dec 2010 - 612-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1365-2990

10.1111/j.1365-2990.2010.01107.x doi


Animals
Anti-Inflammatory Agents
Apoptosis--drug effects
Blotting, Western
Chromatography, High Pressure Liquid
Corpus Striatum--drug effects
DNA Fragmentation
Dopamine--metabolism
Hypoglycemic Agents--pharmacology
Interleukin-1beta--biosynthesis
Interleukin-6--biosynthesis
Iron--antagonists & inhibitors
Lipid Peroxidation--drug effects
Male
Nerve Tissue Proteins--metabolism
Neuroprotective Agents
Oxidative Stress--drug effects
Pioglitazone
RNA, Messenger--biosynthesis
Rats
Rats, Sprague-Dawley
Reverse Transcriptase Polymerase Chain Reaction
Substantia Nigra--drug effects
Thiazolidinediones--pharmacology
alpha-Synuclein--metabolism