Additive effects of C(2)-ceramide on paclitaxel-induced premature senescence of human lung cancer cells.

Chen, Jeff Yi-Fu

Additive effects of C(2)-ceramide on paclitaxel-induced premature senescence of human lung cancer cells. [electronic resource] - Life sciences Sep 2010 - 350-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-0631

10.1016/j.lfs.2010.06.017 doi


Apoptosis--drug effects
Baculoviral IAP Repeat-Containing 3 Protein
Carcinoma, Non-Small-Cell Lung--drug therapy
Caspase 3--metabolism
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
Cellular Senescence--drug effects
Cyclin-Dependent Kinase Inhibitor p21--genetics
DNA Fragmentation--drug effects
Extracellular Signal-Regulated MAP Kinases--metabolism
G2 Phase--drug effects
GTP-Binding Proteins--genetics
Gene Expression--drug effects
Humans
Inhibitor of Apoptosis Proteins--genetics
JNK Mitogen-Activated Protein Kinases--metabolism
Microfilament Proteins--genetics
Muscle Proteins--genetics
Osteonectin--genetics
Paclitaxel--pharmacology
Phosphorylation--drug effects
Plasminogen Activator Inhibitor 1--genetics
Protein Glutamine gamma Glutamyltransferase 2
Proto-Oncogene Proteins c-bcl-2--metabolism
Sphingosine--analogs & derivatives
Transglutaminases--genetics
Ubiquitin-Protein Ligases
beta-Galactosidase--metabolism
p38 Mitogen-Activated Protein Kinases--metabolism