A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair.

Smogorzewska, Agata

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair. [electronic resource] - Molecular cell Jul 2010 - 36-47 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

1097-4164

10.1016/j.molcel.2010.06.023 doi


Amino Acid Sequence
Animals
Caenorhabditis elegans--metabolism
Cell Line
Cross-Linking Reagents--metabolism
DNA Damage
DNA Mismatch Repair--drug effects
DNA Repair--drug effects
Endodeoxyribonucleases
Endonucleases--metabolism
Exodeoxyribonucleases--chemistry
Exonucleases--chemistry
Fanconi Anemia--enzymology
Fanconi Anemia Complementation Group D2 Protein--metabolism
Genetic Testing--methods
Genome, Human--genetics
Humans
Mitomycin--pharmacology
Molecular Sequence Data
Multifunctional Enzymes
Protein Binding--drug effects
Protein Structure, Tertiary
Protein Transport--drug effects
RNA, Small Interfering--metabolism