Oral administration of a PPAR-delta agonist to rodents worsens, not improves, maximal insulin-stimulated glucose transport in skeletal muscle of different fibers.

Cresser, Justin

Oral administration of a PPAR-delta agonist to rodents worsens, not improves, maximal insulin-stimulated glucose transport in skeletal muscle of different fibers. [electronic resource] - American journal of physiology. Regulatory, integrative and comparative physiology Aug 2010 - R470-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1522-1490

10.1152/ajpregu.00431.2009 doi


Administration, Oral
Animals
Biological Transport
Blood Glucose--metabolism
CD36 Antigens--metabolism
Ceramides--metabolism
Dietary Fats--administration & dosage
Diglycerides--metabolism
Fatty Acid-Binding Proteins--metabolism
Female
GTPase-Activating Proteins--metabolism
Glucose Transporter Type 4--metabolism
Glycolysis
Hypoglycemic Agents--administration & dosage
Insulin--metabolism
Insulin Receptor Substrate Proteins--metabolism
Insulin Resistance
Muscle Fibers, Skeletal--drug effects
Oxidation-Reduction
PPAR delta--agonists
Phosphatidylinositol 3-Kinases--metabolism
Phosphorylation
Proto-Oncogene Proteins c-akt--metabolism
Rats
Rats, Sprague-Dawley
Thiazoles--administration & dosage