Pseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer.

Maun, Henry R

Pseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer. [electronic resource] - Biological chemistry Aug 2010 - 881-92 p. digital

Publication Type: Comparative Study; Journal Article; Review

1437-4315

10.1515/BC.2010.098 doi


Animals
Carrier Proteins--metabolism
Catalytic Domain
Drug Design
Hedgehog Proteins--antagonists & inhibitors
Hepatocyte Growth Factor--antagonists & inhibitors
Humans
Ligands
Membrane Glycoproteins--metabolism
Metalloproteases--chemistry
Neoplasms--drug therapy
Patched Receptors
Patched-1 Receptor
Protein Interaction Domains and Motifs
Proto-Oncogene Proteins c-met--metabolism
Receptors, Cell Surface--metabolism
Receptors, Growth Factor--metabolism
Serine Proteases--chemistry
Signal Transduction--drug effects