Everolimus and PTK/ZK show synergistic growth inhibition in the orthotopic BL16/BL6 murine melanoma model.

O'Reilly, Terence

Everolimus and PTK/ZK show synergistic growth inhibition in the orthotopic BL16/BL6 murine melanoma model. [electronic resource] - Cancer chemotherapy and pharmacology Jan 2011 - 193-200 p. digital

Publication Type: Journal Article

1432-0843

10.1007/s00280-010-1307-z doi


Angiogenesis Inhibitors--administration & dosage
Animals
Antineoplastic Combined Chemotherapy Protocols--administration & dosage
Cell Line, Tumor
Dose-Response Relationship, Drug
Drug Synergism
Everolimus
Female
Mechanistic Target of Rapamycin Complex 1
Melanoma, Experimental--drug therapy
Mice
Mice, Inbred C57BL
Models, Biological
Multiprotein Complexes
Neoplasm Metastasis
Phthalazines--administration & dosage
Proteins--antagonists & inhibitors
Pyridines--administration & dosage
Receptors, Vascular Endothelial Growth Factor--antagonists & inhibitors
Sirolimus--administration & dosage
TOR Serine-Threonine Kinases