A common polymorphism in the caspase recruitment domain of RIG-I modifies the innate immune response of human dendritic cells.

Hu, Jianzhong

A common polymorphism in the caspase recruitment domain of RIG-I modifies the innate immune response of human dendritic cells. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Jul 2010 - 424-32 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1550-6606

10.4049/jimmunol.0903291 doi


Animals
CARD Signaling Adaptor Proteins--genetics
Caspases--genetics
Cell Line
Chickens
DEAD Box Protein 58
DEAD-box RNA Helicases--biosynthesis
Dendritic Cells--immunology
Humans
Immunity, Innate--genetics
Interferon-beta--biosynthesis
Newcastle disease virus--immunology
Polymorphism, Single Nucleotide--immunology
Protein Structure, Tertiary--genetics
Receptors, Immunologic
Transcriptional Activation--immunology