Accelerated wound healing by mTOR activation in genetically defined mouse models.

Squarize, Cristiane H

Accelerated wound healing by mTOR activation in genetically defined mouse models. [electronic resource] - PloS one May 2010 - e10643 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Intramural

1932-6203

10.1371/journal.pone.0010643 doi


Animals
Cell Compartmentation--drug effects
Cell Movement--drug effects
Enzyme Activation--drug effects
Epithelial Cells--drug effects
Gene Deletion
Intracellular Signaling Peptides and Proteins--metabolism
Keratinocytes--drug effects
Mice
Models, Animal
PTEN Phosphohydrolase--deficiency
Protein Serine-Threonine Kinases--metabolism
Proto-Oncogene Proteins c-akt--metabolism
Signal Transduction--drug effects
Sirolimus--pharmacology
Skin--drug effects
TOR Serine-Threonine Kinases
Tuberous Sclerosis Complex 1 Protein
Tumor Suppressor Proteins--metabolism
Up-Regulation--drug effects
Wound Healing--drug effects