Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells.

Nautiyal, Jyoti

Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells. [electronic resource] - International journal of cancer Feb 2011 - 951-61 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1097-0215

10.1002/ijc.25410 doi


Adenoma--drug therapy
Adenomatous Polyposis Coli Protein--physiology
Animals
Antineoplastic Agents--pharmacology
Blotting, Western
CSK Tyrosine-Protein Kinase
Cell Adhesion
Cell Movement
Cell Proliferation--drug effects
Cell Transformation, Neoplastic--drug effects
Cells, Cultured
Colonic Neoplasms--drug therapy
Curcumin--pharmacology
Dasatinib
Drug Synergism
Electrophoretic Mobility Shift Assay
Endothelium, Vascular--cytology
ErbB Receptors--metabolism
Female
Humans
Immunoenzyme Techniques
Intestinal Neoplasms--drug therapy
Mice
Mice, Knockout
NF-kappa B--genetics
Neoplasm Invasiveness
Neovascularization, Pathologic
Protein Kinase Inhibitors--pharmacology
Protein-Tyrosine Kinases--metabolism
Pyrimidines--pharmacology
RNA, Messenger--genetics
Receptor, IGF Type 1--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Thiazoles--pharmacology
Umbilical Veins--cytology
src-Family Kinases