Insulin-like growth factor-1 induces phosphorylation of PI3K-Akt/PKB to potentiate proliferation of smooth muscle cells in human saphenous vein.

Jia, Guanghong

Insulin-like growth factor-1 induces phosphorylation of PI3K-Akt/PKB to potentiate proliferation of smooth muscle cells in human saphenous vein. [electronic resource] - Experimental and molecular pathology Aug 2010 - 20-6 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1096-0945

10.1016/j.yexmp.2010.04.002 doi


3-Phosphoinositide-Dependent Protein Kinases
Aged
Cell Proliferation--drug effects
Cells, Cultured
Enzyme-Linked Immunosorbent Assay
Female
Humans
Immunoblotting
Insulin-Like Growth Factor I--pharmacology
Male
Mammary Arteries--cytology
Middle Aged
Muscle, Smooth, Vascular--drug effects
Phosphatidylinositol 3-Kinases--metabolism
Phosphorylation
Protein Serine-Threonine Kinases--metabolism
Proto-Oncogene Proteins c-akt--metabolism
Receptor, IGF Type 1--metabolism
Saphenous Vein--cytology