Sulforaphane- and phenethyl isothiocyanate-induced inhibition of aflatoxin B1-mediated genotoxicity in human hepatocytes: role of GSTM1 genotype and CYP3A4 gene expression.

Gross-Steinmeyer, Kerstin

Sulforaphane- and phenethyl isothiocyanate-induced inhibition of aflatoxin B1-mediated genotoxicity in human hepatocytes: role of GSTM1 genotype and CYP3A4 gene expression. [electronic resource] - Toxicological sciences : an official journal of the Society of Toxicology Aug 2010 - 422-32 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1096-0929

10.1093/toxsci/kfq135 doi


Aflatoxin B1--pharmacokinetics
Cells, Cultured
Cytochrome P-450 CYP3A--genetics
DNA Adducts--analysis
DNA Repair
Genotype
Glutathione Transferase--genetics
Hepatocytes--drug effects
Humans
Isothiocyanates--pharmacology
RNA, Messenger--analysis
Reverse Transcriptase Polymerase Chain Reaction
Sulfoxides
Thiocyanates--pharmacology