Deficiency of XIAP leads to sensitization for Chlamydophila pneumoniae pulmonary infection and dysregulation of innate immune response in mice.

Prakash, Hridayesh

Deficiency of XIAP leads to sensitization for Chlamydophila pneumoniae pulmonary infection and dysregulation of innate immune response in mice. [electronic resource] - The Journal of biological chemistry Jun 2010 - 20291-302 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M109.096297 doi


Animals
Apoptosis--drug effects
CD4-Positive T-Lymphocytes--cytology
CD8-Positive T-Lymphocytes--cytology
Cell Survival--drug effects
Chlamydophila Infections--genetics
Chlamydophila pneumoniae--genetics
DNA, Bacterial--genetics
Flow Cytometry
Host-Pathogen Interactions
Immunity, Innate
Lipopolysaccharides--pharmacology
Lung--metabolism
Lymphocyte Count
Macrophages--cytology
Mice
Mice, Inbred C57BL
Mice, Knockout
Nitric Oxide--metabolism
Polymerase Chain Reaction
Salmonella Infections--genetics
Salmonella typhimurium--physiology
Tumor Necrosis Factor-alpha--metabolism
X-Linked Inhibitor of Apoptosis Protein--deficiency