Construction of a humanized antibody to hepatitis B surface antigen by specificity-determining residues (SDR)-grafting and de-immunization.

Kim, Keun-Soo

Construction of a humanized antibody to hepatitis B surface antigen by specificity-determining residues (SDR)-grafting and de-immunization. [electronic resource] - Biochemical and biophysical research communications May 2010 - 231-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1090-2104

10.1016/j.bbrc.2010.04.071 doi


Amino Acid Sequence
Animals
Antibodies, Monoclonal--chemistry
Antibody Affinity
Epitope Mapping
Epitopes, T-Lymphocyte--chemistry
Hepatitis B--immunology
Hepatitis B Antibodies--chemistry
Hepatitis B Surface Antigens--immunology
Humans
Mice
Molecular Sequence Data
Neutralization Tests
Protein Structure, Secondary