Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome.

Ng, Jeffrey

Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome. [electronic resource] - Gastroenterology Aug 2010 - 542-52, 552.e1-3 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1528-0012

10.1053/j.gastro.2010.04.005 doi


Animals
Apoptosis Regulatory Proteins
Bacterial Proteins--genetics
Bacterial Toxins--genetics
Biopsy
CARD Signaling Adaptor Proteins
Carrier Proteins--genetics
Caspase 1--metabolism
Cell Line
Clostridioides difficile--genetics
Cytoskeletal Proteins--deficiency
Disease Models, Animal
Endocytosis
Endosomes--immunology
Enterotoxins--genetics
Humans
Ileitis--immunology
Ileum--drug effects
Immunity, Innate--drug effects
Inflammation Mediators--metabolism
Interleukin 1 Receptor Antagonist Protein--pharmacology
Interleukin-1beta--metabolism
Macrophages--drug effects
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Knockout
Mutation
NLR Family, Pyrin Domain-Containing 3 Protein