Generating pancreatic beta-cells from embryonic stem cells by manipulating signaling pathways.

Champeris Tsaniras, Spyridon

Generating pancreatic beta-cells from embryonic stem cells by manipulating signaling pathways. [electronic resource] - The Journal of endocrinology Jul 2010 - 13-26 p. digital

Publication Type: Journal Article

1479-6805

10.1677/JOE-10-0073 doi


Animals
Cell Differentiation--drug effects
Diabetes Mellitus, Type 1--surgery
Embryonic Stem Cells--cytology
Hedgehog Proteins--physiology
Humans
Insulin--metabolism
Insulin Secretion
Insulin-Secreting Cells--cytology
Islets of Langerhans Transplantation
Phosphatidylinositol 3-Kinases--physiology
Phosphoinositide-3 Kinase Inhibitors
Receptors, Notch--physiology
Signal Transduction
Transforming Growth Factor beta--physiology
Wnt Proteins--physiology
beta Catenin--physiology