A new cell-based innate immune receptor assay for the examination of receptor activity, ligand specificity, signalling pathways and the detection of pyrogens.

Burger-Kentischer, Anke

A new cell-based innate immune receptor assay for the examination of receptor activity, ligand specificity, signalling pathways and the detection of pyrogens. [electronic resource] - Journal of immunological methods Jun 2010 - 93-103 p. digital

Publication Type: Journal Article

1872-7905

10.1016/j.jim.2010.03.020 doi


Alkaline Phosphatase--genetics
Animals
Diglycerides--pharmacology
Gene Expression--drug effects
Genes, Reporter--genetics
Humans
Immunity, Innate--immunology
Immunologic Tests--methods
Ligands
Lipid A--pharmacology
Lipopeptides--pharmacology
Lipopolysaccharides--pharmacology
Mice
Myeloid Differentiation Factor 88--antagonists & inhibitors
NF-kappa B--antagonists & inhibitors
NIH 3T3 Cells
Nitriles--pharmacology
Oligopeptides--pharmacology
Pyrogens--analysis
Receptors, Pattern Recognition--genetics
Signal Transduction--drug effects
Sulfones--pharmacology
Toll-Like Receptor 1--agonists
Toll-Like Receptor 2--agonists
Toll-Like Receptor 4--agonists
Toll-Like Receptor 6--agonists
Transfection
Zymosan--pharmacology