Curcumin induces down-regulation of EZH2 expression through the MAPK pathway in MDA-MB-435 human breast cancer cells.

Hua, Wen-Feng

Curcumin induces down-regulation of EZH2 expression through the MAPK pathway in MDA-MB-435 human breast cancer cells. [electronic resource] - European journal of pharmacology Jul 2010 - 16-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-0712

10.1016/j.ejphar.2010.03.051 doi


Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Breast Neoplasms--enzymology
Cell Line, Tumor
Cell Proliferation--drug effects
Curcumin--pharmacology
DNA-Binding Proteins--biosynthesis
Down-Regulation--drug effects
Enhancer of Zeste Homolog 2 Protein
Extracellular Signal-Regulated MAP Kinases--metabolism
Female
Gene Expression Regulation, Neoplastic--drug effects
Humans
JNK Mitogen-Activated Protein Kinases--metabolism
MAP Kinase Signaling System--drug effects
Polycomb Repressive Complex 2
Transcription Factors--biosynthesis
p38 Mitogen-Activated Protein Kinases--metabolism