Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.
Tan, Sandra Min-Li
Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jul 2010 - 285-93 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1521-0103
10.1124/jpet.110.165498 doi
Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
Blotting, Western
Carcinoma, Hepatocellular
Cell Line, Tumor
Cell Proliferation--drug effects
Escin--pharmacology
Humans
Immunohistochemistry
Janus Kinase 2--antagonists & inhibitors
Liver Neoplasms
Phosphorylation
STAT3 Transcription Factor--antagonists & inhibitors
Signal Transduction--drug effects
Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jul 2010 - 285-93 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1521-0103
10.1124/jpet.110.165498 doi
Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
Blotting, Western
Carcinoma, Hepatocellular
Cell Line, Tumor
Cell Proliferation--drug effects
Escin--pharmacology
Humans
Immunohistochemistry
Janus Kinase 2--antagonists & inhibitors
Liver Neoplasms
Phosphorylation
STAT3 Transcription Factor--antagonists & inhibitors
Signal Transduction--drug effects