Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilization.

Buron, Nelly

Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilization. [electronic resource] - PloS one Mar 2010 - e9924 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0009924 doi


Animals
Biphenyl Compounds--pharmacology
Cell Line, Tumor
Cross-Linking Reagents--pharmacology
Female
Gene Expression Regulation, Neoplastic
Humans
Membrane Potentials
Mice
Mice, Inbred BALB C
Mitochondria--metabolism
Mitochondrial Membranes--drug effects
Nitrophenols--pharmacology
Peptide Fragments--chemistry
Permeability
Piperazines--pharmacology
Proto-Oncogene Proteins--chemistry
Proto-Oncogene Proteins c-bcl-2--metabolism
Sulfonamides--pharmacology