Rapamycin induces autophagy and exacerbates metabolism associated complications in a mouse model of type 1 diabetes.

Zhou, Zhengyu

Rapamycin induces autophagy and exacerbates metabolism associated complications in a mouse model of type 1 diabetes. [electronic resource] - Indian journal of experimental biology Jan 2010 - 31-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0019-5189


Animals
Autophagy--drug effects
Caspase 3--metabolism
Diabetes Mellitus, Experimental--drug therapy
Diabetes Mellitus, Type 1--drug therapy
Humans
Immunosuppressive Agents--toxicity
Insulin-Secreting Cells--drug effects
Male
Mice
Mice, Inbred C57BL
Microscopy, Electron, Transmission
Sirolimus--toxicity