In vivo silencing of Reptin blocks the progression of human hepatocellular carcinoma in xenografts and is associated with replicative senescence.

Ménard, Ludovic

In vivo silencing of Reptin blocks the progression of human hepatocellular carcinoma in xenografts and is associated with replicative senescence. [electronic resource] - Journal of hepatology May 2010 - 681-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1600-0641

10.1016/j.jhep.2009.12.029 doi


ATPases Associated with Diverse Cellular Activities
Animals
Apoptosis--drug effects
Carcinoma, Hepatocellular--pathology
Carrier Proteins--drug effects
Cell Division--drug effects
Cell Line, Tumor
Cellular Senescence--drug effects
DNA Helicases--drug effects
DNA Primers
Doxycycline--pharmacology
Gene Expression Regulation, Neoplastic--drug effects
Gene Silencing
Genes, Reporter--drug effects
Humans
Liver Neoplasms--pathology
Luciferases--genetics
Mice
Mice, Inbred NOD
Mice, SCID
RNA, Neoplasm--genetics
RNA, Small Interfering--genetics
Reverse Transcriptase Polymerase Chain Reaction
Transplantation, Heterologous