2-Arylureidophenyl-4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)triazines as highly potent and selective ATP competitive mTOR inhibitors: optimization of human microsomal stability.

Verheijen, Jeroen C

2-Arylureidophenyl-4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)triazines as highly potent and selective ATP competitive mTOR inhibitors: optimization of human microsomal stability. [electronic resource] - Bioorganic & medicinal chemistry letters Apr 2010 - 2648-53 p. digital

Publication Type: Journal Article

1464-3405

10.1016/j.bmcl.2010.02.031 doi


Animals
Humans
Inhibitory Concentration 50
Mice
Microsomes--drug effects
Transplantation, Heterologous
Triazines--chemistry