Hepatic metabolism and transporter gene variants enhance response to rosuvastatin in patients with acute myocardial infarction: the GEOSTAT-1 Study.

Bailey, Kristian M

Hepatic metabolism and transporter gene variants enhance response to rosuvastatin in patients with acute myocardial infarction: the GEOSTAT-1 Study. [electronic resource] - Circulation. Cardiovascular genetics Jun 2010 - 276-85 p. digital

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

1942-3268

10.1161/CIRCGENETICS.109.898502 doi


ATP Binding Cassette Transporter, Subfamily G, Member 2
ATP-Binding Cassette Transporters--genetics
Aged
Cholesterol, LDL--blood
Cytochrome P-450 CYP3A--genetics
Cytochrome P-450 Enzyme System--genetics
Female
Fluorobenzenes--therapeutic use
Genotype
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors--therapeutic use
Liver-Specific Organic Anion Transporter 1
Male
Middle Aged
Myocardial Infarction--drug therapy
Neoplasm Proteins--genetics
Odds Ratio
Organic Anion Transporters--genetics
Polymorphism, Single Nucleotide
Pyrimidines--therapeutic use
Regression Analysis
Rosuvastatin Calcium
Simvastatin--therapeutic use
Sulfonamides--therapeutic use