An adenoviral vaccine encoding full-length inactivated human Her2 exhibits potent immunogenicty and enhanced therapeutic efficacy without oncogenicity.

Hartman, Zachary C

An adenoviral vaccine encoding full-length inactivated human Her2 exhibits potent immunogenicty and enhanced therapeutic efficacy without oncogenicity. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Mar 2010 - 1466-77 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1557-3265

10.1158/1078-0432.CCR-09-2549 doi


Adenoviridae
Animals
Blotting, Western
Cancer Vaccines--immunology
Cell Separation
Female
Flow Cytometry
Genes, erbB-2--genetics
Genetic Therapy--methods
Genetic Vectors
Humans
Mammary Neoplasms, Experimental--genetics
Mice
Mice, Transgenic
Oligonucleotide Array Sequence Analysis
Receptor, ErbB-2--genetics
Reverse Transcriptase Polymerase Chain Reaction
Vaccination--methods