Repeat instability as the basis for human diseases and as a potential target for therapy.

López Castel, Arturo

Repeat instability as the basis for human diseases and as a potential target for therapy. [electronic resource] - Nature reviews. Molecular cell biology Mar 2010 - 165-70 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

1471-0080

10.1038/nrm2854 doi


Animals
Base Sequence
DNA Damage--drug effects
DNA Repair--drug effects
DNA Replication--drug effects
Drug Therapy--methods
Genetic Predisposition to Disease--genetics
Genomic Instability--drug effects
Humans
Mice
Models, Biological
Transcription, Genetic--drug effects
Trinucleotide Repeat Expansion--genetics
Trinucleotide Repeats--genetics