BMP-3 promotes mesenchymal stem cell proliferation through the TGF-beta/activin signaling pathway.

Stewart, Aaron

BMP-3 promotes mesenchymal stem cell proliferation through the TGF-beta/activin signaling pathway. [electronic resource] - Journal of cellular physiology Jun 2010 - 658-66 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1097-4652

10.1002/jcp.22064 doi


3T3-L1 Cells
Activins--metabolism
Adipocytes--cytology
Animals
Benzamides--pharmacology
Bone Morphogenetic Protein 3--pharmacology
Cell Differentiation--drug effects
Cell Lineage--drug effects
Cell Proliferation--drug effects
Dioxoles--pharmacology
Enzyme Activation--drug effects
Extracellular Signal-Regulated MAP Kinases--metabolism
Gene Knockdown Techniques
Humans
MAP Kinase Signaling System--drug effects
Male
Mesenchymal Stem Cells--cytology
Mice
RNA, Small Interfering--metabolism
Rats
Rats, Wistar
Signal Transduction--drug effects
Smad2 Protein--metabolism
Transforming Growth Factor beta--metabolism
p38 Mitogen-Activated Protein Kinases--metabolism