Autophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stress.

Shin, Yong-Joo

Autophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stress. [electronic resource] - Arthritis research & therapy 2010 - R19 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1478-6362

10.1186/ar2921 doi


Arthritis, Rheumatoid--metabolism
Autophagy--drug effects
Blotting, Western
Caspase 3--drug effects
Cell Survival--drug effects
Down-Regulation
Endoplasmic Reticulum--drug effects
Endoplasmic Reticulum Chaperone BiP
Enzyme Inhibitors--toxicity
Fibroblasts--drug effects
Gene Expression--drug effects
Humans
Osteoarthritis--metabolism
RNA, Small Interfering
Synovial Membrane--drug effects
Thapsigargin--toxicity
Transcription Factor CHOP--biosynthesis
Transfection