SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation.

Thomsen, Martin K

SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation. [electronic resource] - Cancer research Feb 2010 - 979-87 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1538-7445

10.1158/0008-5472.CAN-09-2370 doi


Adult
Animals
Cell Proliferation
Epithelium--metabolism
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Homeodomain Proteins--genetics
Humans
Immunohistochemistry
Kaplan-Meier Estimate
Ki-67 Antigen--metabolism
Male
Mice
Mice, Knockout
Mice, Transgenic
PTEN Phosphohydrolase--genetics
Prostate--metabolism
Prostatic Neoplasms--genetics
Reverse Transcriptase Polymerase Chain Reaction
SOX9 Transcription Factor--genetics
Tissue Array Analysis
Transcription Factors--genetics