Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegeneration.

Song, C

Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegeneration. [electronic resource] - Molecular pharmacology Apr 2010 - 621-32 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1521-0111

10.1124/mol.109.062174 doi


Acetylation
Anacardic Acids--pharmacology
Animals
Antioxidants--pharmacology
Apoptosis--drug effects
CREB-Binding Protein--analysis
Caspase 3--metabolism
Cells, Cultured
Dieldrin--toxicity
Environmental Pollutants--toxicity
Epigenesis, Genetic
Histones--metabolism
Insecticides--toxicity
Male
Mesencephalon--drug effects
Mice
Mice, Inbred C57BL
Neurodegenerative Diseases--chemically induced
Neuroprotective Agents--pharmacology
Proteasome Inhibitors
Protein Kinase C-delta--metabolism
Rats