Absence of the alpha v beta 3 integrin dictates the time-course of angiogenesis in the hypoxic central nervous system: accelerated endothelial proliferation correlates with compensatory increases in alpha 5 beta 1 integrin expression.

Li, Longxuan

Absence of the alpha v beta 3 integrin dictates the time-course of angiogenesis in the hypoxic central nervous system: accelerated endothelial proliferation correlates with compensatory increases in alpha 5 beta 1 integrin expression. [electronic resource] - Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism May 2010 - 1031-43 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1559-7016

10.1038/jcbfm.2009.276 doi


Animals
Cell Adhesion
Cell Proliferation
Cells, Cultured
Central Nervous System--blood supply
Collagen Type I--metabolism
Collagen Type IV--metabolism
Endothelial Cells--cytology
Endothelium, Vascular--cytology
Hypoxia--metabolism
Integrin alpha5beta1--genetics
Integrin alphaVbeta3--genetics
Mice
Mice, Inbred C57BL
Mice, Knockout
Neovascularization, Physiologic--physiology
Vitronectin--metabolism