A phase I dose-escalation, safety and pharmacokinetic study of the 2-methoxyestradiol analog ENMD-1198 administered orally to patients with advanced cancer.

Zhou, Qing

A phase I dose-escalation, safety and pharmacokinetic study of the 2-methoxyestradiol analog ENMD-1198 administered orally to patients with advanced cancer. [electronic resource] - Investigational new drugs Apr 2011 - 340-6 p. digital

Publication Type: Clinical Trial, Phase I; Journal Article

1573-0646

10.1007/s10637-009-9383-9 doi


2-Methoxyestradiol
Administration, Oral
Adult
Aged
Animals
Antineoplastic Agents--administration & dosage
Demography
Dogs
Dose-Response Relationship, Drug
Estradiol--administration & dosage
Estrenes--administration & dosage
Female
Humans
Male
Middle Aged
Neoplasms--blood
Rats
Species Specificity