Millisecond timescale fluctuations in dihydrofolate reductase are exquisitely sensitive to the bound ligands.
Boehr, David D
Millisecond timescale fluctuations in dihydrofolate reductase are exquisitely sensitive to the bound ligands. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jan 2010 - 1373-8 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1091-6490
10.1073/pnas.0914163107 doi
Escherichia coli--enzymology
Ligands
Models, Molecular
NADP--chemistry
Nuclear Magnetic Resonance, Biomolecular
Protein Binding
Protein Structure, Tertiary
Substrate Specificity
Tetrahydrofolate Dehydrogenase--chemistry
Tetrahydrofolates--genetics
Thermodynamics
Time Factors
Millisecond timescale fluctuations in dihydrofolate reductase are exquisitely sensitive to the bound ligands. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jan 2010 - 1373-8 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1091-6490
10.1073/pnas.0914163107 doi
Escherichia coli--enzymology
Ligands
Models, Molecular
NADP--chemistry
Nuclear Magnetic Resonance, Biomolecular
Protein Binding
Protein Structure, Tertiary
Substrate Specificity
Tetrahydrofolate Dehydrogenase--chemistry
Tetrahydrofolates--genetics
Thermodynamics
Time Factors