Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COS(phox) cells.

Nie, Baoming

Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COS(phox) cells. [electronic resource] - Cellular signalling May 2010 - 770-82 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1873-3913

10.1016/j.cellsig.2010.01.001 doi


Amino Acid Substitution--genetics
Animals
COS Cells
Cell Membrane--drug effects
Chlorocebus aethiops
Enzyme Activation--drug effects
Feedback, Physiological--drug effects
GTP-Binding Protein beta Subunits--metabolism
GTP-Binding Protein gamma Subunits--metabolism
Guanine Nucleotide Exchange Factors--chemistry
Humans
Mice
Models, Biological
Mutation--genetics
N-Formylmethionine Leucyl-Phenylalanine--pharmacology
NADPH Oxidases--metabolism
Phosphatidylinositol 3-Kinases--metabolism
Protein Kinase C-delta--metabolism
Protein Structure, Tertiary
Proto-Oncogene Proteins c-akt--metabolism
Superoxides--metabolism
rac1 GTP-Binding Protein--metabolism