Partial silencing of methyl cytosine protein binding 2 (MECP2) in mesenchymal stem cells induces senescence with an increase in damaged DNA.

Squillaro, Tiziana

Partial silencing of methyl cytosine protein binding 2 (MECP2) in mesenchymal stem cells induces senescence with an increase in damaged DNA. [electronic resource] - FASEB journal : official publication of the Federation of American Societies for Experimental Biology May 2010 - 1593-603 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1530-6860

10.1096/fj.09-143057 doi


Cell Cycle--genetics
Cells, Cultured
Cellular Senescence--genetics
Cytosine--metabolism
DNA Damage
DNA Methylation
DNA Repair--genetics
Down-Regulation
Gene Silencing
Humans
Mesenchymal Stem Cells--physiology
Methyl-CpG-Binding Protein 2--genetics
Retinoblastoma Protein--metabolism
Tumor Suppressor Protein p53--metabolism