High-throughput assay to measure oxygen consumption in digitonin-permeabilized cells of patients with mitochondrial disorders.

Jonckheere, An I

High-throughput assay to measure oxygen consumption in digitonin-permeabilized cells of patients with mitochondrial disorders. [electronic resource] - Clinical chemistry Mar 2010 - 424-31 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Validation Study

1530-8561

10.1373/clinchem.2009.131441 doi


Cell Membrane Permeability
Cell Respiration
Cells, Cultured
Digitonin
Fibroblasts--metabolism
Fluorescence
High-Throughput Screening Assays--methods
Humans
Malates--metabolism
Mitochondria, Muscle--metabolism
Mitochondrial Diseases--diagnosis
Oxygen Consumption
Pyruvic Acid--metabolism