A study of the effects of substituents on the selectivity of the binding of N-arylaminomethylene malonate inhibitors to DHODH.
Cowen, Deborah
A study of the effects of substituents on the selectivity of the binding of N-arylaminomethylene malonate inhibitors to DHODH. [electronic resource] - Bioorganic & medicinal chemistry letters Feb 2010 - 1284-7 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
1464-3405
10.1016/j.bmcl.2009.11.079 doi
Aniline Compounds--chemistry
Animals
Crotonates
Dihydroorotate Dehydrogenase
Humans
Hydroxybutyrates--chemistry
Malonates--chemistry
Nitriles
Oxidoreductases Acting on CH-CH Group Donors--antagonists & inhibitors
Plasmodium falciparum--drug effects
Protein Binding--physiology
Rats
Toluidines
A study of the effects of substituents on the selectivity of the binding of N-arylaminomethylene malonate inhibitors to DHODH. [electronic resource] - Bioorganic & medicinal chemistry letters Feb 2010 - 1284-7 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
1464-3405
10.1016/j.bmcl.2009.11.079 doi
Aniline Compounds--chemistry
Animals
Crotonates
Dihydroorotate Dehydrogenase
Humans
Hydroxybutyrates--chemistry
Malonates--chemistry
Nitriles
Oxidoreductases Acting on CH-CH Group Donors--antagonists & inhibitors
Plasmodium falciparum--drug effects
Protein Binding--physiology
Rats
Toluidines