Alpha1-syntrophin mutations identified in sudden infant death syndrome cause an increase in late cardiac sodium current.

Cheng, Jianding

Alpha1-syntrophin mutations identified in sudden infant death syndrome cause an increase in late cardiac sodium current. [electronic resource] - Circulation. Arrhythmia and electrophysiology Dec 2009 - 667-76 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1941-3084

10.1161/CIRCEP.109.891440 doi


Animals
Calcium-Binding Proteins--genetics
Cell Line
DNA Mutational Analysis
Enzyme Inhibitors--pharmacology
Female
Genotype
Humans
Infant
Infant, Newborn
Ion Channel Gating
Long QT Syndrome--genetics
Male
Membrane Potentials
Membrane Proteins--genetics
Mice
Muscle Proteins--drug effects
Mutation, Missense
Myocardium--metabolism
NAV1.5 Voltage-Gated Sodium Channel
Nitric Oxide Synthase--antagonists & inhibitors
Nitric Oxide Synthase Type I
Open Reading Frames
Patch-Clamp Techniques
Phenotype
Plasma Membrane Calcium-Transporting ATPases--metabolism
Rats
Sodium--metabolism
Sodium Channels--drug effects
Sudden Infant Death--genetics
Time Factors
Transfection