RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice.

Kim, Sang-Soo

RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice. [electronic resource] - Molecular therapy : the journal of the American Society of Gene Therapy Feb 2010 - 370-6 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1525-0024

10.1038/mt.2009.271 doi


Animals
Gene Silencing--physiology
HIV Infections--genetics
Leukocytes--metabolism
Liposomes--therapeutic use
Lymphocyte Function-Associated Antigen-1--genetics
Mice
Nanoparticles--therapeutic use
RNA Interference
RNA, Small Interfering--genetics
Receptors, CCR5--genetics
Reverse Transcriptase Polymerase Chain Reaction