A serine cluster mediates BMAL1-dependent CLOCK phosphorylation and degradation.

Spengler, Mary L

A serine cluster mediates BMAL1-dependent CLOCK phosphorylation and degradation. [electronic resource] - Cell cycle (Georgetown, Tex.) Dec 2009 - 4138-46 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1551-4005

10.4161/cc.8.24.10273 doi


ARNTL Transcription Factors--chemistry
Amino Acid Sequence--genetics
Animals
Biological Clocks--physiology
CLOCK Proteins--chemistry
Catalytic Domain--genetics
Cell Line
Circadian Rhythm--physiology
Fibroblasts--metabolism
Gene Expression Regulation--physiology
Glycogen Synthase Kinase 3--metabolism
Glycogen Synthase Kinase 3 beta
Humans
Mice
Mice, Inbred C57BL
Mice, Knockout
Phosphorylation
Promoter Regions, Genetic--genetics
Regulatory Elements, Transcriptional--genetics
Serine--metabolism
Transcription Factors--genetics
Up-Regulation--genetics