Trichloroethylene induces dopaminergic neurodegeneration in Fisher 344 rats.

Liu, Mei

Trichloroethylene induces dopaminergic neurodegeneration in Fisher 344 rats. [electronic resource] - Journal of neurochemistry Feb 2010 - 773-83 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1471-4159

10.1111/j.1471-4159.2009.06497.x doi


Animals
CD11b Antigen--metabolism
Caspase 3--metabolism
Choline O-Acetyltransferase--metabolism
Chromatography, High Pressure Liquid--methods
Disease Models, Animal
Dopamine--metabolism
Dopamine and cAMP-Regulated Phosphoprotein 32--metabolism
Dose-Response Relationship, Drug
Electrochemistry--methods
Encephalitis--chemically induced
Gene Expression Regulation--drug effects
Male
Mitochondria--drug effects
Neurodegenerative Diseases--chemically induced
Oxidative Stress--drug effects
Rats
Rats, Inbred F344
Rotarod Performance Test
Solvents--toxicity
Substantia Nigra--metabolism
Trichloroethylene--toxicity
Tyrosine--analogs & derivatives
Tyrosine 3-Monooxygenase--metabolism
alpha-Synuclein--metabolism