Zl-n-91, a selective phosphodiesterase 4 inhibitor, suppresses inflammatory response in a COPD-like rat model.
Wang, Ya-juan
Zl-n-91, a selective phosphodiesterase 4 inhibitor, suppresses inflammatory response in a COPD-like rat model. [electronic resource] - International immunopharmacology Feb 2010 - 252-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1878-1705
10.1016/j.intimp.2009.11.008 doi
Animals
Anti-Inflammatory Agents, Non-Steroidal--chemistry
Cyclic Nucleotide Phosphodiesterases, Type 4--immunology
Disease Models, Animal
Furans--chemistry
Lipopolysaccharides--immunology
Lung--drug effects
Male
Matrix Metalloproteinase 9--immunology
Matrix Metalloproteinase Inhibitors
Neutrophils--drug effects
Peroxidase--drug effects
Phenyl Ethers--chemistry
Phosphodiesterase 4 Inhibitors
Phosphodiesterase Inhibitors--chemistry
Pulmonary Disease, Chronic Obstructive--drug therapy
Rats
Rats, Sprague-Dawley
Smoking--adverse effects
Zl-n-91, a selective phosphodiesterase 4 inhibitor, suppresses inflammatory response in a COPD-like rat model. [electronic resource] - International immunopharmacology Feb 2010 - 252-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1878-1705
10.1016/j.intimp.2009.11.008 doi
Animals
Anti-Inflammatory Agents, Non-Steroidal--chemistry
Cyclic Nucleotide Phosphodiesterases, Type 4--immunology
Disease Models, Animal
Furans--chemistry
Lipopolysaccharides--immunology
Lung--drug effects
Male
Matrix Metalloproteinase 9--immunology
Matrix Metalloproteinase Inhibitors
Neutrophils--drug effects
Peroxidase--drug effects
Phenyl Ethers--chemistry
Phosphodiesterase 4 Inhibitors
Phosphodiesterase Inhibitors--chemistry
Pulmonary Disease, Chronic Obstructive--drug therapy
Rats
Rats, Sprague-Dawley
Smoking--adverse effects