Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues.
Prazeres, Verónica F V
Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues. [electronic resource] - Journal of medicinal chemistry Jan 2010 - 191-200 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/jm9010466 doi
Alcohols--chemical synthesis
Binding, Competitive
Crystallography, X-Ray
Enzyme Inhibitors--chemical synthesis
Helicobacter pylori--enzymology
Hydro-Lyases--antagonists & inhibitors
Models, Molecular
Molecular Structure
Structure-Activity Relationship
Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues. [electronic resource] - Journal of medicinal chemistry Jan 2010 - 191-200 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/jm9010466 doi
Alcohols--chemical synthesis
Binding, Competitive
Crystallography, X-Ray
Enzyme Inhibitors--chemical synthesis
Helicobacter pylori--enzymology
Hydro-Lyases--antagonists & inhibitors
Models, Molecular
Molecular Structure
Structure-Activity Relationship