Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis.

Yang, Jingxian

Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis. [electronic resource] - The Journal of clinical investigation Dec 2009 - 3678-91 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1558-8238

10.1172/JCI37914 doi


Adult Stem Cells--cytology
Animals
Apoptosis
Cell Differentiation
Encephalomyelitis, Autoimmune, Experimental--immunology
Fas Ligand Protein--metabolism
Female
Genetic Engineering
Green Fluorescent Proteins--genetics
Immunomodulation
In Vitro Techniques
Interleukin-10--biosynthesis
Mice
Mice, Inbred C57BL
Mice, Transgenic
Multipotent Stem Cells--cytology
Nerve Fibers, Myelinated--immunology
Neurons--cytology
Recombinant Proteins--genetics
T-Lymphocytes--immunology
Time Factors
Transduction, Genetic
fas Receptor--metabolism