Salmonella enterica serovar typhimurium trxA mutants are protective against virulent challenge and induce less inflammation than the live-attenuated vaccine strain SL3261.

Peters, S E

Salmonella enterica serovar typhimurium trxA mutants are protective against virulent challenge and induce less inflammation than the live-attenuated vaccine strain SL3261. [electronic resource] - Infection and immunity Jan 2010 - 326-36 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1098-5522

10.1128/IAI.00768-09 doi


Animals
Bacterial Proteins--genetics
Inflammation--chemically induced
Injections, Intravenous
Lipopolysaccharides
Liver--pathology
Mice
Mice, Inbred BALB C
Mice, Knockout
Mutation
Salmonella Infections, Animal--pathology
Salmonella Vaccines--administration & dosage
Salmonella typhimurium--genetics
Spleen--pathology
Time Factors
Toll-Like Receptor 4--genetics
Virulence