Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cells.
Backer, Joseph M
Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cells. [electronic resource] - Neoplasia (New York, N.Y.) Nov 2009 - 1165-73 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1476-5586
10.1593/neo.09878 doi
Animals
Antineoplastic Agents--pharmacology
Bacterial Toxins--pharmacology
Blotting, Western
Breast Neoplasms--drug therapy
Drug Synergism
Endoplasmic Reticulum--drug effects
Endoplasmic Reticulum Chaperone BiP
Epidermal Growth Factor--pharmacology
Female
Heat-Shock Proteins--drug effects
Humans
Immunohistochemistry
Male
Mice
Microscopy, Fluorescence
Neoplasms, Experimental--drug therapy
Prostatic Neoplasms--drug therapy
Protein Folding--drug effects
Recombinant Fusion Proteins--pharmacology
Stress, Physiological--drug effects
Xenograft Model Antitumor Assays
Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cells. [electronic resource] - Neoplasia (New York, N.Y.) Nov 2009 - 1165-73 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1476-5586
10.1593/neo.09878 doi
Animals
Antineoplastic Agents--pharmacology
Bacterial Toxins--pharmacology
Blotting, Western
Breast Neoplasms--drug therapy
Drug Synergism
Endoplasmic Reticulum--drug effects
Endoplasmic Reticulum Chaperone BiP
Epidermal Growth Factor--pharmacology
Female
Heat-Shock Proteins--drug effects
Humans
Immunohistochemistry
Male
Mice
Microscopy, Fluorescence
Neoplasms, Experimental--drug therapy
Prostatic Neoplasms--drug therapy
Protein Folding--drug effects
Recombinant Fusion Proteins--pharmacology
Stress, Physiological--drug effects
Xenograft Model Antitumor Assays