A hypersensitive estrogen receptor alpha mutation that alters dynamic protein interactions.

Herynk, Matthew H

A hypersensitive estrogen receptor alpha mutation that alters dynamic protein interactions. [electronic resource] - Breast cancer research and treatment Jul 2010 - 381-93 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1573-7217

10.1007/s10549-009-0580-1 doi


Animals
BRCA1 Protein--metabolism
Binding Sites
Breast Neoplasms--genetics
Cell Line, Tumor
Cell Proliferation
Co-Repressor Proteins--metabolism
Estradiol--metabolism
Estrogen Receptor alpha--genetics
Female
Humans
Ligands
Mice
Mice, Nude
Mutation
Neoplasms, Hormone-Dependent--genetics
Nuclear Receptor Coactivator 2--metabolism
Nuclear Receptor Coactivator 3--metabolism
Ovariectomy
Promoter Regions, Genetic
Radioligand Assay
Recombinant Fusion Proteins--metabolism
TATA-Box Binding Protein--metabolism
Time Factors
Transcription Factor TFIIB--metabolism
Transfection
Trefoil Factor-1
Tumor Burden
Tumor Suppressor Proteins--genetics