Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction.
Hennige, Anita M
Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction. [electronic resource] - Diabetes Jan 2010 - 119-27 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1939-327X
10.2337/db09-0512 doi
Animals
Apoptosis
Blood Glucose--metabolism
Cell Culture Techniques
Cell Death
Diet
Forkhead Box Protein O1
Forkhead Transcription Factors--genetics
Gene Expression Regulation
Glucose Intolerance--prevention & control
Insulin--analysis
Insulin Secretion
Insulin-Secreting Cells--enzymology
Mice
Mice, Knockout
Mice, Transgenic
Mitochondria--drug effects
Protein Kinase C-delta--deficiency
Rhodamine 123--pharmacology
Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction. [electronic resource] - Diabetes Jan 2010 - 119-27 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1939-327X
10.2337/db09-0512 doi
Animals
Apoptosis
Blood Glucose--metabolism
Cell Culture Techniques
Cell Death
Diet
Forkhead Box Protein O1
Forkhead Transcription Factors--genetics
Gene Expression Regulation
Glucose Intolerance--prevention & control
Insulin--analysis
Insulin Secretion
Insulin-Secreting Cells--enzymology
Mice
Mice, Knockout
Mice, Transgenic
Mitochondria--drug effects
Protein Kinase C-delta--deficiency
Rhodamine 123--pharmacology