Noradrenaline induces IL-1ra and IL-1 type II receptor expression in primary glial cells and protects against IL-1beta-induced neurotoxicity.

McNamee, Eoin N

Noradrenaline induces IL-1ra and IL-1 type II receptor expression in primary glial cells and protects against IL-1beta-induced neurotoxicity. [electronic resource] - European journal of pharmacology Jan 2010 - 219-28 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-0712

10.1016/j.ejphar.2009.09.054 doi


Animals
Cyclic AMP--metabolism
Cyclic AMP-Dependent Protein Kinases--metabolism
Enzyme Activation--drug effects
Extracellular Signal-Regulated MAP Kinases--metabolism
Interleukin 1 Receptor Antagonist Protein--genetics
Interleukin-1beta--toxicity
Microglia--drug effects
Neuroglia--drug effects
Neurons--drug effects
Norepinephrine--pharmacology
Rats
Rats, Wistar
Receptors, Adrenergic, beta--metabolism
Receptors, Interleukin-1 Type II--genetics
Signal Transduction--drug effects
Transcriptional Activation--drug effects