Fluoroquinolones lower constitutive H2AX and ATM phosphorylation in TK6 lymphoblastoid cells via modulation of the intracellular redox status.

Halicka, H Dorota

Fluoroquinolones lower constitutive H2AX and ATM phosphorylation in TK6 lymphoblastoid cells via modulation of the intracellular redox status. [electronic resource] - Pharmacological reports : PR - 711-8 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural

2299-5684

10.1016/s1734-1140(09)70124-0 doi


Cells, Cultured
DNA Damage--drug effects
Fluoroquinolones--chemistry
Histones--metabolism
Humans
Intracellular Fluid--drug effects
Lymphocyte Activation--drug effects
Lymphocytes--cytology
Oxidation-Reduction--drug effects
Phosphatidylinositol 3-Kinases--metabolism
Phosphorylation--drug effects
Reactive Oxygen Species--metabolism